- 询价
- Miltenyi Biotec
- 德国
- 130-124-075
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TCR Vα7.2
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA179
- 标记物：
PerCP-Vio 700
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
TCR Vα7.2 Antibody, anti-human, REAfinity™
- 抗体名：
TCR Vα7.2 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of TCR Vα7.2+ cells by flow cytometryClone REA179 recognizes the TCR chain Vα7.2, which together with Jα33 segment forms the invariant T cell receptor. Human Vα7.2-Jα33 invariant T cells are preferentially localized in the gut and are often termed as mucosal-associated T (MAIT) cells. MAIT cells are restricted to MHC class I like molecules, such as MR1. Further, MAIT cells are suggested to be involved in regulation of immune response at the mucosal surfaces, which are the primary sites for pathogen entry. | Additional information: Clone REA179 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Treiner, E. et al. (2003) Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422 (6928): 164–169. | Wang, Y. et al. (2016) Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J. Exp. Med. 213 (11): 2413–2435. | Qualai, J. et al. (2016) Expression of CD11c is associated with unconventional activated T cell subsets with high migratory potential. PLoS One 11 (4): e0154253. | Gold, M. C. and Lewinsohn, D. M. (2013) Co-dependents: MR1-restricted MAIT cells and their antimicrobial function. Nat. Rev. Microbiol. 11 (1): 14–19.
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TCR Vα7.2 Antibody, anti-human, PerCP-Vio® 700, REAfinity™, 30 tests in 60 µL
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