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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Slan (M-DC8)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1050
- 标记物:
APC
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 浓度:
1:50
- 抗体英文名:
Slan (M-DC8) Antibody, anti-human, REAfinity™
- 抗体名:
Slan (M-DC8) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of slan (M-DC8)+ cells by flow cytometryClone REA1050 recognizes the human 6-sulfo LacNAc (Slan) (M-DC8) antigen, which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14low monocytes. Slan (M-DC8)+ cells constitute 0.5–2% of all PBMCs with similar frequencies among mononuclear cells from cord blood. | Additional information: Clone REA1050 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Schäkel, K. et al. (1998) A novel dendritic cell population in human blood: one-step immunomagnetic isolation by a specific mAb (M-DC8) and in vitro priming of cytotoxic T lymphocytes. Eur. J. Immunol. 28: 4084–4093. | de Baey, A. et al. (2001) Phenotype and function of human dendritic cells derived from M-DC8+ monocytes. Eur. J. Immunol. 31: 1646–1655. | Schäkel, K. et al. (2002) 6-Sulfo LacNAc, a novel carbohydrate modification of PSGL-1, defines an inflammatory type of human dendritic cells. Immunity 17: 289–301.
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Slan (M-DC8) Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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