- 询价
- Miltenyi Biotec
- 德国
- 130-112-335
- 2025年12月09日
- Flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Siglec-F
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA798
- 标记物：
APC-Vio 770
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
Siglec-F Antibody, anti-mouse, REAfinity™
- 抗体名：
Siglec-F Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 200 µL
Identification and enumeration of siglec-F+ cells by flow cytometryClone REA798 recognizes the mouse siglec-F antigen, also kown as Siglec-5, which belongs to the siglec family (sialic acid-binding immunoglobulin-type lectins). Siglecs are expressed on immune cells and are a subset of the I-type lectins. Siglec-F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. In mouse, siglec-F is an inhibitory receptor on eosinophils. | Additional information: Clone REA798 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Tateno, H. et al. (2005) Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15 (11): 1125–1135. | Zhang, M. et al. (2007) Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 109 (10): 4280–4287. | Guo, J. P. et al. (2011) Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs. Am. J. Respir. Cell Mol. Biol. 44 (2): 238–243.
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Siglec-F Antibody, anti-mouse, APC-Vio® 770, REAfinity™, 30 µg in 200 µL
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