SHIP-1 Antibody, anti-human/mouse, APC, REAfinity™, 100 tests in 1 mL
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SHIP-1 Antibody, anti-human/mo

use, APC, REAfinity™, 100 tests in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-109-155
  • 2025年12月09日
  • Intracellular flow cytometry
  • human cell line
  • human, mouse
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      SHIP-1

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      REA580

    • 标记物

      APC

    • 适应物种

      human, mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Intracellular flow cytometry

    • 浓度

      1:10

    • 抗体英文名

      SHIP-1 Antibody, anti-human/mouse, REAfinity™

    • 抗体名

      SHIP-1 Antibody, anti-human/mouse, REAfinity™

    • 规格

      100 tests in 1 mL

    Identification and enumeration of SHIP-1+ cells by flow cytometryClone REA580 recognizes the human and mouse SHIP-1 antigen, which is a 145 kDa protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. SHIP-1, also known as enzyme phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1, is expressed on hematopoietic cells, including immature CD34+ cells, the majority of T cells, and a minority of B cells. It has a negative effect on cell growth and therefore loss or modification may have profound effects on hematopoietic cell development. Thus SHIP-1 functions as a negative regulator of myeloid cell proliferation and survival. | Additional information: Clone REA580 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Geier, S. J. et al. (1997) The human SHIP gene is differentially expressed in cell lineages of the bone marrow and blood. Blood 89 (6): 1876–1885. | Ware, M. D. et al. (1996) Cloning and characterization of human SHIP, the 145-kD inositol 5-phosphatase that associates with SHC after cytokine stimulation. Blood 88 (8): 2833–2840. | Drayer, A. L. et al. (1996) Cloning and expression of a human placenta inositol 1,3,4,5-tetrakisphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase. Biochem. Biophys. Res. Commun. 225 (1): 243–249.
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    SHIP-1 Antibody, anti-human/mouse, APC, REAfinity™, 100 tests in 1 mL
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