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P2X7R Antibody, anti-mouse, Bi

otin, REAfinity™, 150 µg in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-114-220
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      P2X7R

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      REA875

    • 标记物

      Biotin

    • 适应物种

      mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      P2X7R Antibody, anti-mouse, REAfinity™

    • 抗体名

      P2X7R Antibody, anti-mouse, REAfinity™

    • 规格

      150 µg in 1 mL

    Identification and enumeration of P2X7R+ cells by flow cytometryClone REA875 recognizes the mouse P2X7R antigen, also known as P2RX7 or P2X7 (P2X purinoceptor 7), which is a receptor for ATP that acts as a ligand-gated ion channel. P2X7R is involved in different inflammatory, immune, neurologic, and musculoskeletal disorders and is able to modulate LPS-induced macrophage production of inflammatory mediators. P2X7R is found on cells of the immune system, e.g., mast cells, microglia, macrophages, T cells, and B cells, in uterine endometrium, retina, and in the central and peripheral nervous systems. | Additional information: Clone REA875 displays negligible binding to Fc receptors.

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    图标文献和实验
    该产品被引用文献
    Chessell, I. P. et al. (1998) Cloning and functional characterisation of the mouse P2X7 receptor. FEBS Lett. 439 (1-2): 26–30. | Kawano, A. et al. (2012) Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages. Biochem. Biophys. Res. Commun. 419 (2): 374–380. | Alves, L. A. et al. (2014) The P2X7 receptor: shifting from a low- to a high-conductance channel - an enigmatic phenomenon? Biochim. Biophys. Acta 1838 (10): 2578–2587. | Bartlett, R. et al. (2014) The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease. Pharmacol. Rev. 66 (3): 638–675.
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    P2X7R Antibody, anti-mouse, Biotin, REAfinity™, 150 µg in 1 mL
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