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p16 Antibody, anti-human, FITC

, REAfinity™, 30 tests in 60 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-116-239
  • 2025年12月09日
  • Intracellular flow cytometry
  • human cell line
  • human
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      p16

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      REA973

    • 标记物

      FITC

    • 适应物种

      human

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Intracellular flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      p16 Antibody, anti-human, REAfinity™

    • 抗体名

      p16 Antibody, anti-human, REAfinity™

    • 规格

      30 tests in 60 µL

    Identification and enumeration of p16+ cells by flow cytometryClone REA973 recognizes the human p16 protein, a member of the cyclin-dependent kinases (CDKs), also known as cyclin-dependent kinase 4 inhibitor (CDKN2) or INK4A. p16 is a multiple tumor-suppressor protein that functions as a negative regulator of the proliferation of normal cells and tumorigenesis by forming heterodimers with CDK4 and CDK6. p16 is found in most of different cell types but it is not detected in brain or skeletal muscle. | Additional information: Clone REA973 displays negligible binding to Fc receptors

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    图标文献和实验
    该产品被引用文献
    Serrano, M. et al. (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366 (6456): 704–707. | Okamoto, A. et al. (1994) Mutations and altered expression of p16INK4 in human cancer. Proc. Natl. Acad. Sci. U.S.A. 91 (23): 11045–11049. | Bockstaele, L. et al. (2006) Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors". Mol. Cell. Biol. 26 (13): 5070–5085. | Huang, X. et al. (2007) Identification and characterization of a novel protein ISOC2 that interacts with p16INK4a. Biochem. Biophys. Res. Commun. 361 (2): 287–293.
    相关实验
    • Anti-GFP/BrdU In Situ Immunostaining

      Dilute 1 µL fresh streptavidin-Alexa Flour 555 in 1 mL PBS (1:1,000).  Spin the dilute antibody at high speed for 30'  to remove particulates.  Add supernatant to specimen and incubate 30' at room temp.  Remove antibody and add 1 mL PBS.  O.K

    • AbC Anti-Mouse Bead Kit

      实验步骤   1.  Using the AbC Anti-Mouse Bead Kit 1)        Completely resuspend the AbC capture beads (Component A) and negative beads (Component B) by gently vortexing for 30 seconds before use. 2)        Label

    • AbC Anti-Rat/Hamster Bead Kit

      1 μL   5)      Label another sample tube for each fluorochrome-conjugated antibody you are using, and add 1 drop of AbC capture beads (Component A in the AbC Anti-Mouse Bead Kit) to each tube. 6)     

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    文献支持
    p16 Antibody, anti-human, FITC, REAfinity™, 30 tests in 60 µL
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