- 询价
- Miltenyi Biotec
- 德国
- 130-104-298
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, mouse, other
企业认证
相关产品推荐更多 >
IgG Antibody, anti-human, FITC, 30 tests in 60 µL
询价
CD49b Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 1 mL
询价
Ki-67 Antibody, anti-human/mouse, Vio® R667, REAfinity™, 100 tests in 200 µL
询价
ELK-1 pS383 Antibody, anti-human, FITC, REAfinity™, 100 tests in 200 µL
询价CD310 (VEGFR-3) Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
p120 Catenin pT310
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA153
- 标记物：
PE-Vio 770
- 适应物种：
human, mouse, other
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 抗体英文名：
p120 Catenin pT310 Antibody, anti-human, REAfinity™
- 抗体名：
p120 Catenin pT310 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of p120 catenin pT310+ cells by flow cytometryClone REA153 recognizes the threonine residue (T310)-phosphorylated form of p120 Catenin, a prototypic member of subfamily of Armadillo-domain (ARM) proteins. p120 ARM domain displays 22% homology to other ARM-domain proteins such as β-catenin and plakoglobin, which are basically cadherin binding proteins, suggesting the involvement of p120 in binding to cadherin. p120 associates with most classical (type I) and nonclassical (type II) cadherins via ARM repeats 1–7 and is localised at the cell junctions, where it constitutes the cadherin complex. Functions of p120 include regulation of stability of cadherins and modulation of activity of rho GTPases in the cytoplasm. Furthermore, lack of p120 Catenin in mouse leads to tumor development, suggesting its further role as tumor supressor. Phosphorylation of p120 Catenin at multiple sites regulates its various functions and it can be phosphorylated by Src and various receptor tyrosine kinases. | Additional information: Clone REA153 displays negligible binding to Fc receptors.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Liu, X. et al. (2014) Interactions between MUC1 and p120 catenin regulate dynamic features of cell adhesion, motility and metastasis. Cancer Res. 74 (5): 1609–1620. | Stairs, D. B. et al. (2011) Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell 19 (4): 470–483. | Reynolds, A. B. et al. (2004) Emerging roles for p120-catenin in cell adhesion and cancer. Oncogene 23 (48): 7947–7956.
技术资料暂无技术资料 索取技术资料
文献支持
p120 Catenin pT310 Antibody, anti-human, PE-Vio® 770, REAfinity™, 100 tests in 1 mL
询价
