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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
OSMRβ
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA837
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
OSMRβ Antibody, anti-human, REAfinity™
- 抗体名:
OSMRβ Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of OSMRβ+ cells by flow cytometryClone REA837 recognizes the human Anti-OSMRβ antigen, the β subunit of the Oncostatin-M-specific receptor (OSMR). OSMRβ belongs to the IL-6 receptor family and is activated by Oncostatin-M. Its expression is up-regulated by IFN-γ and bacterial lipopolysaccharides (LPS). OSMRβ is found in high levels in all neural cells as well as in fibroblast, in epithelial cells, and in a variety of tumor cell lines. OSM is most closely related to leukemia inhibitory factor (LIF) and it utilizes the LIF receptor in addition to its specific receptor in the human. | Additional information: Clone REA837 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Mosley, B. et al. (1996) Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. J. Biol. Chem. 271 (51): 32635–32643. | Tanaka, M. and Miyajima, A. (2003) Oncostatin M, a multifunctional cytokine. Rev. Physiol. Biochem. Pharmacol. 149: 39–52.
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OSMRβ Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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