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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
NK1.1
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1162
- 标记物:
PerCP-Vio 700
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
NK1.1 Antibody, anti-mouse, REAfinity™
- 抗体名:
NK1.1 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of NK1.1+ cells by flow cytometryClone REA1162 recognizes the mouse NK1.1 antigen, a single-pass type II membrane protein also known as CD161 or killer cell lectin-like receptor subfamily B member 1. NK1.1 is expressed by natural killer cells and a subset of T cells in the mouse strains C57BL/6, FVB/N, and NZB, but not in the mouse strains AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. It plays a stimulatory role on natural killer cells cytotoxicity. Activation by cross-linking of the receptor induces Ca 2)+ mobilization and interferon-gamma production. | Additional information: Clone REA1162 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Giorda, R. et al. (1992) Genomic structure and strain-specific expression of the natural killer cell receptor NKR-P1. J Immunol 149 (6): 1957–1963. | Stenström, M. et al. (2005) Natural killer T-cell populations in C57BL/6 and NK1.1 congenic BALB.NK mice-a novel thymic subset defined in BALB.NK mice. Immunology 114 (3): 336–345. | Ruiz, A. L. et al. (2014) NK1.1+ CD8+ T cells escape TGF-β control and contribute to early microbial pathogen response. Nat Commun 5: 5150.
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NK1.1 Antibody, anti-mouse, PerCP-Vio® 700, REAfinity™, 30 µg in 200 µL
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