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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Nur77
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA704
- 标记物:
PE
- 适应物种:
human, mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
Nur77 Antibody, anti-mouse, REAfinity™
- 抗体名:
Nur77 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of Nur77+ cells by flow cytometryClone REA704 recognizes the mouse Nur77 antigen, a member of the steroid/ thyroid hormone receptor superfamily of intracellular transcription factors. Nur77 is an inducible orphan nuclear receptor also known as NR4A1 or nerve growth factor IB (NGFI-B) and plays a role in cell cycle mediation, inflammation, and apoptosis and is involved in mediation of inflammatory responses in macrophages. Nur77 expression is found on thymocytes and T cell lines and is mainly expressed in testis but also in brain and muscle tissue. | Additional information: Clone REA704 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Cunningham, N. R. et al. (2006) Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation. J Immunol 177 (10): 6660–6666. | Pei, L. et al. (2006) Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol Endocrinol. 20 (4): 786–794. | Tao, R. et al. (2008) Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival. PLoS One 3 (5): e2321.
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Nur77 Antibody, anti-mouse, PE, REAfinity™, 30 µg in 200 µL
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