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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
MICA/MICB
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1076
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
MICA/MICB Antibody, anti-human, REAfinity™
- 抗体名:
MICA/MICB Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of MICA/MICB+ cells by flow cytometryClone REA1076 recognizes MICA and MICB, which are transmembrane glycoproteins related to major histocompatibility complex (MHC) class I molecules. In contrast to other MHC class I proteins, MICA and MICB have no association with β2-microglobulin and do not bind peptides. They are ligands for NKG2D, which is expressed on NK cells and many T cells. MICA and MICB are expressed on endothelial cells and fibroblasts and are stress-induced in epithelial cells. | Additional information: Clone REA1076 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Houchins, J. P. et al. (1991) DNA sequence analysis of NKG2, a family of related cDNA clones encoding type II integral membrane proteins on human natural killer cells. J. Exp. Med. 173 (4): 1017–1020. | Bauer, S. et al. (1999) Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285: 727–729. | Li, P. et al. (1999) Crystal structure of the MHC class I homolog MIC-A, a γδ T cell ligand. Immunity 10: 577–584.
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MICA/MICB Antibody, anti-human, Biotin, REAfinity™, 30 tests in 60 µL
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