- 询价
- Miltenyi Biotec
- 德国
- 130-104-478
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Nanog
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA297
- 标记物：
FITC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:11
- 抗体英文名：
Nanog Antibody, anti-mouse, REAfinity™
- 抗体名：
Nanog Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of Nanog+ cells by flow cytometryClone REA297 recognizes the murine Nanog antigen, a homeobox transcription factor also known as ES cell-associated protein 4. Nanog is thought to be a key factor in maintaining pluripotency. It is expressed in the central portion of the morula, the inner cell mass of the blastocyst, in embryonic stem cells (ESC) and embryonic germ cells (EGC). The expression decreases with ESC differentiation. Nanog is thought to function in concert with other factors such as Oct-4 and SOX2 to establish ESC identity. Overexpression of Nanog in mouse ESC causes them to self-renew in the absence of Leukemia inhibitory factor. Loss of Nanog function causes differentiation of mouse ESC into other cell types. | Additional information: Clone REA297 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Mitsui, K. et al. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113: 631–642. | Lin, T. et al. (2005) p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat. Cell Biol. 7 (2): 165–171. | Yates, A. et al. (2005) The homeodomain protein Nanog and pluripotency in mouse embryonic stem cells. Biochem. Soc. Trans. 33 (6): 1518–1521.
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Nanog Antibody, anti-mouse, FITC, REAfinity™, 30 µg in 1 mL
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