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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Melanoma (MCSP)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1041
- 标记物:
VioBlue
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
Melanoma (MCSP) Antibody, anti-human, REAfinity™
- 抗体名:
Melanoma (MCSP) Antibody, anti-human, REAfinity™
- 规格:
30 tests in 60 µL
Identification and enumeration of melanoma (MCSP)+ cells by flow cytometryClone REA1041 recognizes the melanoma-associated chondroitin sulfate proteoglycan (MCSP) antigen, also known as high molecular weight melanoma-associated antigen. | It has been reported, that Melanoma has a high amino acid sequence homology with AN2 and NG2. MCSP is expressed on the majority (>90%) of human melanoma tissues and melanoma cell lines but not on carcinoma cells, fibroblastoid cells, and cells of hematopoietic origin. | Additional information: Clone REA1041 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Morgan, A. C. et al. (1981) Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma 1: 27–36. | Bumol, T. F. and Reisfeld, R. A. (1982) Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc. Natl. Acad. Sci. U.S.A. 79 (4): 1245–1249. | Bumol, T. F. et al. (1984) Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans. J. Biol. Chem. 259 (20): 12733–12741. | Pluschke, G. et al. (1996) Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan. Proc. Natl. Acad. Sci. U.S.A. 93 (18): 9710–9715. | Benez, A. et al. (1999) Detection of circulating melanoma cells by immunomagnetic cell sorting. J. Clin. Lab. Anal. 13: 229–233. | Siewert, C. et al. (2001) Rapid enrichment and detection of melanoma cells from peripheral blood mononuclear cells by a new assay combining immunomagnetic cell sorting and immunocytochemical staining. Recent Results Cancer Res. 158: 51–60. | Paul, A. K. et al. (2009) Expression of HMP/AN2, a melanoma associated antigen, in murine cerebral gliomas: potential for radioimmunotargeting. J Neurooncol. 94 (1): 21–30.
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Melanoma (MCSP) Antibody, anti-human, VioBlue®, REAfinity™, 30 tests in 60 µL
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