- 询价
- Miltenyi Biotec
- 德国
- 130-126-528
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
LRP-4
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA552
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
LRP-4 Antibody, anti-human, REAfinity™
- 抗体名：
LRP-4 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of LRP-4+ cells by flow cytometryClone REA552 recognizes the human LRP-4 antigen, a β-propeller containing protein, which is a member of the low density lipoprotein-receptor gene family and a modulator of extracellular cell signaling pathways in development. LRP-4 is expressed in bone and cultured osteoblasts and binds Dkk1 and sclerostin in vitro. It plays a physiological role in the regulation of bone growth and turnover. | Additional information: Clone REA552 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Holdsworth, G. et al. (2012) Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors. J. Biol. Chem. 287 (32): 26464–26477. | Leupin, O. et al. (2011) Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function. J. Biol. Chem. 286 (22): 19489–19500. | Choi, H. Y. et al. (2009) Lrp4, a novel receptor for Dickkopf 1 and sclerostin, is expressed by osteoblasts and regulates bone growth and turnover in vivo. PLoS One 4 (11): e7930.
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LRP-4 Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
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