- 询价
- Miltenyi Biotec
- 德国
- 130-111-453
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Integrin β6
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA748
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
Integrin β6 Antibody, anti-human, REAfinity™
- 抗体名：
Integrin β6 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of integrin β6+ cells by flow cytometryClone REA748 recognizes the human integrin β6 antigen, a 95 kDa type I transmembrane glycoprotein which is a member of the integrin β family. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. Integrin β6, also known as ITGB6, is a receptor for fibronectin and cytotactin and interacts with coxsackievirus A9 and coxsackievirus B1 proteins. Integrin β6 forms heterodimers with integrin αV. Internalisation of integrin αV/β6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. | Additional information: Clone REA748 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Agrez, M. V. et al. (1997) Integrin alpha v beta 6 enhances coxsackievirus B1 lytic infection of human colon cancer cells. Virology 239 (1): 71–77. | Ramsay, A. G. et al. (2007) HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. Cancer Res. 67 (11): 5275–5284. | Gianni, T. et al. (2013) αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion. PLoS Pathog. 9 (12): .
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Integrin β6 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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