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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
JAML
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA862
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 抗体英文名:
JAML Antibody, anti-mouse, REAfinity™
- 抗体名:
JAML Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of JAML+ cells by flow cytometryClone REA862 recognizes the mouse JAML antigen, also known as AMICA1 or junctional adhesion molecule-like protein. JAML is a transmembrane protein, which consists of two extracellular immunoglobulin-like domains, a membrane-spanning region, and a cytoplasmic tail involved in activation signaling. JAML is found on γ/δ intraepithelial T cells. The costimulatory molecule JAML binds to its ligands Coxsackie virus and adenovirus receptor (CAR), that leads to cellular proliferation and cytokine and growth factor production. | Additional information: Clone REA862 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Zen, K. et al. (2005) Neutrophil migration across tight junctions is mediated by adhesive interactions between epithelial coxsackie and adenovirus receptor and a junctional adhesion molecule-like protein on neutrophils. Mol. Biol. Cell 16 (6): 2694–2703. | Witherden, D. A. et al. (2010) The junctional adhesion molecule JAML is a costimulatory receptor for epithelial gammadelta T cell activation. Science 329 (5996): 1205–1210.
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JAML Antibody, anti-mouse, APC, REAfinity™, 30 µg in 200 µL
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