- 询价
- Miltenyi Biotec
- 德国
- 130-110-549
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Jak1
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA700
- 标记物：
PE
- 适应物种：
human, mouse, rat
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
Jak1 Antibody, anti-human/mouse/rat, REAfinity™
- 抗体名：
Jak1 Antibody, anti-human/mouse/rat, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of Jak1+ cells by flow cytometryClone REA700 recognizes the human, mouse, and rat Jak1 antigen, also known as tyrosine-protein kinase JAK1 or janus kinase 1. Jak1 is a widely expressed membrane-associated phosphoprotein characterized by the presence of a second phosphotransferase-related domain immediately N terminal to the PTK domain. Jak1 is involved in the IFN-α/β/γ signal pathway and activates transcription factors of the STAT family by phosphorylating critical tyrosine regulatory sites. | Additional information: Clone REA700 displays negligible binding to Fc receptors
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文献和实验该产品被引用文献
Wilks, A. F. et al. (1991) Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase. Mol. Cell. Biol. 11 (4): 2057–2065. | Williams, N. K. et al. (2009) Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase Domains. J. Mol. Biol. 387 (1): 219–232.
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Jak1 Antibody, anti-human/mouse/rat, PE, REAfinity™, 100 tests in 200 µL
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