- 询价
- Miltenyi Biotec
- 德国
- 130-111-859
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IL-17F
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA666
- 标记物：
FITC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:50
- 抗体英文名：
IL-17F Antibody, anti-mouse, REAfinity™
- 抗体名：
IL-17F Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of IL-17F+ cells by flow cytometryClone REA666 recognizes the mouse interleukin 17F (IL-17F) antigen, a cytokine which is expressed by a subset of activated T cells in the lamina propria. IL-17F belongs to the IL-17 gene family, which consists of six members (IL-17A, IL-17B, IL-17C, IL-17D, IL-17E, and IL-17F). All members have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape. The isoforms of IL-17F 1 and 2 (ML-1) have the highest homology to IL-17A. It has been reported, that IL-17–producing T lymphocytes comprise a distinct lineage of proinflammatory T helper cells, termed Tʜ17 cells, that are major contributors to autoimmune disease. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of Ag-induced pulmonary inflammation. | Additional information: Clone REA666 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Ivanov, I. I. et al. (2006) The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 126: 1121–1133. | Suzuki, S. et al. (2007) Expression of interleukin-17F in a mouse model of allergic asthma. Int. Arch. Allergy Immunol. 143: 89–94. | Oda, N. et al. (2005) Interleukin-17F induces pulmonary neutrophilia and amplifies antigen-induced allergic response. Am J Respir Crit Care Med. 171 (1): 12–18.
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IL-17F Antibody, anti-mouse, FITC, REAfinity™, 150 µg in 1 mL
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