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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IL-17E
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA952
- 标记物:
PE
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
IL-17E Antibody, anti-mouse, REAfinity™
- 抗体名:
IL-17E Antibody, anti-mouse, REAfinity™
- 规格:
150 µg in 1 mL
Identification and enumeration of IL-17E+ cells by flow cytometryClone REA952 recognizes the mouse interleukin 17E (IL-17E) antigen. IL-17 is a family of pro-inflammatory cytokines that plays a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. IL-17E is suggested to be an important mediator of allergic disease via production of IL-4, IL-5, IL-13, and eotaxin. IL-17E expression is found in low levels in different peripheral tissues, e.g., prostate, testis, trachea, brain, kidney, and lung. | Additional information: Clone REA952 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Fort, M. M. et al. (2001) IL-25 induces IL-4, IL-5, and IL-13 and Tʜ2-associated pathologies in vivo. Immunity 15 (6): 985–995. | Hurst, S. D. et al. (2002) New IL-17 family members promote Tʜ1 or Tʜ2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 169 (1): 443–453. | Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821–852.
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IL-17E Antibody, anti-mouse, PE, REAfinity™, 150 µg in 1 mL
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