- 询价
- Miltenyi Biotec
- 德国
- 130-111-856
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
企业认证
相关产品推荐更多 >
GPR56 Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
询价
CD31 Antibody, anti-human, PE-Vio® 615, REAfinity™, 100 tests in 200 µL
询价
CD49d Antibody, anti-human, PE-Vio® 770, 100 tests in 200 µL
询价CD266 (FN14) Antibody, anti-human/mouse, APC, 30 tests in 300 µL
询价CD24 Antibody, anti-human, PE, REAfinity™, 100 tests in 200 µL
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IL-17A
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA660
- 标记物：
FITC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
IL-17A Antibody, anti-mouse, REAfinity™
- 抗体名：
IL-17A Antibody, anti-mouse, REAfinity™
- 规格：
150 µg in 1 mL
Identification and enumeration of IL-17A+ cells by flow cytometryClone REA660 recognizes mouse interleukin 17A (IL-17A). Interleukin 17 (IL-17) is a family of cytokines that play a central role in adaptive immunity as well as autoinflammatory disorders. Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections. | Recently, a new mouse T helper cell subset has been identified, which is dinstinct from Tʜ1 and Tʜ2 cells: IL-17–producing CD4+ T helper (Tʜ17) cells. Tʜ17 cells preferentially produce IL-17A, IL-17F, IL-21, and IL-22. Receptors for IL-17 and IL-22 are expressed on various epithelial tissues, thus Tʜ17 cells are crucial for the cross-talk between immune system and tissues. It is now established that Tʜ17 cells are responsible for driving autoimmune inflammation. After stimulation of mouse T cells, IL-17 is not only secreted by CD4+ T cells, but also by CD8+ T cells and γδ T cells. | Additional information: Clone REA660 displays negligible binding to Fc receptors.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Kennedy, J. et al. (1996) Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4–CD8–T cells. J. Interferon Cytokine Res. 16 (8): 611–617. | Weaver, C. T. et al. (2007) IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 25: 821–852. | Ouyang, W. et al. (2008) The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 28: 454–467. | Zheng, S. et al. (2017) Human gingiva-derived mesenchymal stem cells ameliorate Streptozoticin-induced T1DM in mice via suppression of T effector cells and up-regulating Treg subsets. Sci Rep 7 (1): 15249.
技术资料暂无技术资料 索取技术资料
文献支持
IL-17A Antibody, anti-mouse, FITC, REAfinity™, 150 µg in 1 mL
询价
