- 询价
- Miltenyi Biotec
- 德国
- 130-133-451
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IL-31
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1363
- 标记物：
Vio B515
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 抗体英文名：
IL-31 Antibody, anti-human, REAfinity™
- 抗体名：
IL-31 Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of IL-31+ cells by flow cytometryClone REA1363 recognizes the human IL-31 protein, which is a member of the gp130/IL-6 cytokine family. Human IL-31 is a cytokine that plays a role in inflammation of the skin. It is preferentially produced by type 2 helper T cells. IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL31RA) and oncostatin M receptor subunits ((OSMRβ). These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. Signaling also involves the JAK/STAT pathway, the PI3 kinase/AKT cascade, and the MAP kinase pathway. | Additional information: Clone REA1363 displays negligible binding to Fc receptors. |
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文献和实验该产品被引用文献
Cornelissen, C. et al. (2012) Signaling by IL-31 and functional consequences. Eur. J. Cell Biol. 91 (6-7): 552–566. | Zhang, Q. et al. (2008) Structures and biological functions of IL-31 and IL-31 receptors. Cytokine Growth Factor Rev. 19 (5-6): 347–356. | Rabenhorst, A. et al. (2014) Interleukin-31: a novel diagnostic marker of allergic disease. Curr. Allergy Asthma Rep. 14 (4): 423.
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IL-31 Antibody, anti-human, Vio® B515, REAfinity™, 100 tests in 200 µL
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