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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IL-10
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1008
- 标记物:
Vio R667
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry
- 浓度:
1:50
- 抗体英文名:
IL-10 Antibody, anti-mouse, REAfinity™
- 抗体名:
IL-10 Antibody, anti-mouse, REAfinity™
- 规格:
30 µg in 200 µL
Identification and enumeration of IL-10+ cells by flow cytometryClone REA1008 recognizes the interleukin-10 (IL-10) cytokine, which is predominantly secreted by CD4+ T cells and antigen-presenting cells, such as monocytes/macrophages and dendritic cells. IL-10 has important suppressive functions on immune responses and is believed to be involved in the maintenance of tolerance. IL-10 blocks activation of cytokine synthesis by Tʜ1 cells, activated monocytes, and NK cells. It can stimulate immunoglobulin production by B cells. | Additional information: Clone REA1008 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Ajuebor, M. N. et al. (1999) Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation. Biochem. Biophys. Res. Commun. 255 (2): 279–282. | Assaman, C. et al. (1999) An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190 (7): 995–1004.
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IL-10 Antibody, anti-mouse, Vio® R667, REAfinity™, 30 µg in 200 µL
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