- 询价
- Miltenyi Biotec
- 德国
- 130-116-992
- 2025年12月09日
- Intracellular flow cytometry, Mass cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
IFN-α
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1013
- 标记物：
FITC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
IFN-α Antibody, anti-human, REAfinity™
- 抗体名：
IFN-α Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of IFN-α+ cells by flow cytometryType I interferons (IFNs), including IFN-α, are a family of cytokines that exert pleiotropic functions in the immune system. Besides its potent antiviral activity, IFN-α exerts a variety of immunomodulatory effects, including positive and negative regulation of its own production, regulation of IL-12 and IFN-γ production, promotion of natural killer (NK) cell cytotoxicity, activation and maturation of dendritic cells, and the promotion of B cell development towards plasma cells. IFN-α is expressed predominantly by CD123+CD11c-CD303 (BDCA2)+ plasmacytoid dendritic cells (pDCs). Clone REA1013 recognizes the majority of the IFN-α subtypes, including IFN-α2b. | Additional information: Clone REA1013 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Ronnblom, L. and Alm, G. V. (2001) An etiopathogenic role for the type I IFN system in SLE. Trends Immunol. 22: 427–431. | Båve, U. et al. (2003) Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. J Immunol 171 (6): 3296–3302.
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文献支持
IFN-α Antibody, anti-human, FITC, REAfinity™, 30 tests in 60 µL
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