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IFNAR2 Antibody, anti-human, V

io® Bright V423, REAfinity™, 100 tests in 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-131-070
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • human
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德国美天旎生物技术有限公司
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原：

      IFNAR2

    • 亚型：

      recombinant human IgG1

    • 形态：

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件：

      避光，2-8℃

    • 克隆性：

      REA124

    • 标记物：

      Vio Bright V423

    • 适应物种：

      human

    • 保质期：

      24个月

    • 供应商：

      Miltenyi Biotec

    • 宿主：

      human cell line

    • 应用范围：

      Flow cytometry

    • 浓度：

      1:50

    • 抗体英文名：

      IFNAR2 Antibody, anti-human, REAfinity™

    • 抗体名：

      IFNAR2 Antibody, anti-human, REAfinity™

    • 规格：

      100 tests in 200 µL

    Identification and enumeration of IFNAR2+ cells by flow cytometryClone REA124 recognizes the human interferon α/β receptor 2 (IFNAR2) antigen, a 100 kDa single-pass type I membrane protein that forms one of the two chains of a receptor for the type I interferons IFN-α, IFN-β, and IFN-ω. These interferons are a group of structurally and functionally related proteins, induced by viruses or double-stranded RNA and defined by their ability to establish an antiviral state in cells. IFNAR2 is expressed on most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression is higher on monocytes and granulocytes than on lymphocytes. It is involved in IFN-mediated STAT1, STAT2, and STAT3 activation. The alternatively spliced isoform of IFNAR2 is a potent inhibitor of type I IFN receptor activity. | Additional information: Clone REA124 displays negligible binding to Fc receptors.

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    该产品被引用文献
    Constantinescu, S. N. et al. (1995) Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex. Proc. Natl. Acad. Sci. U.S.A. 92 (23): 10487–10491. | Novick, D. et al. (1995) Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. J Leukoc Biol 57 (5): 712–718. | Novick, D. et al. (1994) The human interferon alpha/beta receptor: characterization and molecular cloning. Cell 77 (3): 391–400.
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    IFNAR2 Antibody, anti-human, Vio® Bright V423, REAfinity™, 100 tests in 200 µL
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