- 询价
- Miltenyi Biotec
- 德国
- 130-124-305
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
HLA-BC
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA672
- 标记物：
APC
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 抗体英文名：
HLA-BC Antibody, anti-human, REAfinity™
- 抗体名：
HLA-BC Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of HLA-BC+ cells by flow cytometryClone REA672 recognizes the class I human leukocyte antigens (HLA) B and C. Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, one of which comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. | Additional information: Clone REA672 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Parham, P. et al. (1996) Population biology of antigen presentation by MHC class I molecules. Science 272 (5258): 67–74. | Srivastava, R. et al. (1985) Molecular organization of the class I genes of human major histocompatibility complex. Immunol. Rev. 84: 93–121.
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HLA-BC Antibody, anti-human, APC, REAfinity™, 30 tests in 60 µL
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