- 询价
- Miltenyi Biotec
- 德国
- 130-124-521
- 2025年12月09日
- Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- human cell line
- human, mouse, rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Helios
- 亚型：
recombinant human IgG1
- 形态：
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件：
避光，2-8℃
- 克隆性：
REA829
- 标记物：
pure
- 适应物种：
human, mouse, rat
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Mass cytometry
- 抗体英文名：
Helios Antibody, anti-human/mouse, REAfinity™
- 抗体名：
Helios Antibody, anti-human/mouse, REAfinity™
- 规格：
100 µg in 100 µL
Identification and enumeration of Helios+ cells by mass cytometryClone REA829 recognizes mouse and human Helios, which is a zinc-finger transcription factor of the Ikaros family. As well as Ikaros and Aiolos, Helios functions as an important regulator of lymphoid development and differentiation and is involved in the control of gene expression. Helios is found on the earliest haematopoietic sites of the embryo, in adult haemopoietic stem cells, and on regulatory T cells. | Additional information: Clone REA829 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Kelley, C. M. et al. (1998) Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitors. Curr. Biol. 8 (9): 508–515. | Rebollo, A. et al. (2003) Ikaros, Aiolos and Helios: Transcription regulators and lymphoid malignancies. Immunol. Cell Biol. 81: 171–175. | Thornton, A. M. et al. (2010) Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. Curr. Biol. 184: 3433–3441. | Gottschalk, R. A. et al. (2012) Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J Immunol 188: 976–980.
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Helios Antibody, anti-human/mouse, pure, REAfinity™, 100 µg in 100 µL
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