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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
GLAST (ACSA-1)
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA1445
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
GLAST (ACSA-1) Antibody, anti-human, REAfinity™
- 抗体名:
GLAST (ACSA-1) Antibody, anti-human, REAfinity™
- 规格:
200 µL
Detection of GLAST (ACSA-1)+ cellsClone REA1445 recognizes the GLAST (ACSA-1), astrocyte cell surface antigen-1), a specific extracellular epitope of the astrocyte specific transmembrane glycoprotein GLAST in the central nervous system (CNS). Besides GLT-1, GLAST (ACSA-1) is the most abundant glutamate transporter and is predominantly expressed by astrocytes in the developing and neonatal mammalian CNS. Also radial glia, which belong to the astrocyte lineage and play important roles in development, are known to express GLAST (ACSA-1). Postnatally, radial glia only persist in a few regions, such as Bermann glia in the cerebellum, Müller glia in the retina, and radial glia in the dentate gyrus of the adult hippocampus. |
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文献和实验该产品被引用文献
Storck, T. et al. (1992) Structure, expression, and functional analysis of a Na+-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. U.S.A. 8 (22): 10955–10959. | Wahle, S. and Stoffel, W. (1996) Membrane topology of the high-affinity L-glutamate transporter (GLAST- 1) of the central nervous system. J. Cell Biol. 135 (6): 1867–1877. | Kimelberg, H. K. (2004) The problem of astrocyte identity. Neurochem. Int. 45 (2-3): 191–202. | Morris, L. G. et al. (2013) Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat. Genet. 45 (3): 253–261. | Jackson, W. S. et al. (2014) Translation of the prion protein mRNA is robust in astrocytes but does not amplify during reactive astrocytosis in the mouse brain. PLoS One 9 (4): e95958.
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GLAST (ACSA-1) Antibody, anti-human, PE, REAfinity™, 200 µL
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