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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
GFAP
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA335
- 标记物:
APC
- 适应物种:
human, mouse, rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 抗体英文名:
GFAP Antibody, anti-human/mouse/rat, REAfinity™
- 抗体名:
GFAP Antibody, anti-human/mouse/rat, REAfinity™
- 规格:
100 tests in 200 µL
Identification and enumeration of GFAP+ cells by flow cytometryClone REA335 recognizes the human, mouse, and rat glial fibrillary acidic protein (GFAP), the main intermediate filament protein in mature astrocytes and an important component of the cytoskeleton in astrocytes during development. GFAP is expressed exclusively in astrocytes in the central nervous system. It has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity, and reactive gliosis. Moreover, different subpopulations of astrocytes have been identified, which are likely to have distinctive tasks in brain physiology and pathology, and which are not only classified by their spatial and temporal appearance, but also by their specific expression of intermediate filaments, including distinct GFAP isoforms. | Additional information: Clone REA335 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Reeves, S. A. et al. (1989) Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc. Natl. Acad. Sci. U.S.A. 86 (13): 5178–5182. | Baba, H. et al. (1997) GFAP gene expression during development of astrocyte. Dev. Neurosci. 19 (1): 49–57. | Middeldorp, J. et al. (2011) GFAP in health and disease. Prog. Neurobiol. 93 (3): 421–443.
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GFAP Antibody, anti-human/mouse/rat, APC, REAfinity™, 100 tests in 200 µL
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