- 询价
- Miltenyi Biotec
- 德国
- 130-102-174
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- mouse
企业认证
相关产品推荐更多 >
DLL4 Antibody, anti-human, FITC, 100 tests in 200 µL
询价CD65 Antibody, anti-human, APC-Vio® 770, 30 tests in 300 µL
询价CD133/1 Antibody, anti-human, Vio® Bright FITC, 30 tests in 60 µL
询价
TCRα/β Antibody, anti-human, PerCP-Vio® 700, 100 tests in 200 µL
询价iNKT Antibody, anti-human, PE-Vio® 770, 30 tests in 60 µL
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
GARP (LRRC32)
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA139
- 标记物：
APC
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:10
- 抗体英文名：
GARP (LRRC32) Antibody, anti-mouse, REAfinity™
- 抗体名：
GARP (LRRC32) Antibody, anti-mouse, REAfinity™
- 规格：
30 µg in 1 mL
Identification and enumeration of GARP (LRRC32)+ cells by flow cytometryClone REA139 recognizes murine GARP, a 80 KDa type I membrane glycoprotein which belongs to the family of leucine rich repeat proteins. Expression of GARP protein is found on megakaryocytes and platelets. Activated GARP has been found to be associated with latency associated peptide (LAP), the prodomain responsible for conferring latency to nonactive TGFβ. Thus, GARP as a latent TGFβ binding protein (LTBP) regulates the surface expression of TGFβ and serves as a carrier of LAP, at the cell surface, to immune response active sites, where TGFβ is eventually activated and released to exert further physiological functions such as differentiation of regulatory T cells. | Additional information: Clone REA139 displays negligible binding to Fc receptors. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Tran, D. Q. et al. (2009) GARP (LRRC32) is essential for the surface expression of latent TGF-β on platelets and activated FOXP3+ regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 106: 13445–13450. | Battaglia, M. et al. (2009) The Tregs' world according to GARP. Eur. J. Immunol. 39 (12): 3296–3300. | Vermeersch, E. et al. (2017) The role of platelet and endothelial GARP in thrombosis and hemostasis. PLoS One 12 (13): e0173329. | Wang, R. et al. (2008) Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression. PLoS One 3 (7): e2705. | Ollendorff, V. et al. (1994) The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth Differ. 5: 213–219.
技术资料暂无技术资料 索取技术资料
文献支持
GARP (LRRC32) Antibody, anti-mouse, APC, REAfinity™, 30 µg in 1 mL
询价
