- 询价
- Miltenyi Biotec
- 德国
- 130-124-001
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
FoxA2
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA506
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:50
- 抗体英文名：
FoxA2 Antibody, anti-human, REAfinity™
- 抗体名：
FoxA2 Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of FoxA2+ cells by flow cytometryClone REA506 recognizes the human forkhead box A2 (FoxA2) antigen, a transcription factor which is also known as hepatocyte nuclear factor 3β (HNF-3β). FoxA2 is involved in embryonic development, establishment of tissue-specific gene expression, and regulation of gene expression in differentiated tissues. It is thought to act as a pioneer factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. In embryonic development, FoxA2 is required for notochord formation. It is involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas, and lungs. FoxA2 is also involved in glucose homeostasis. It regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. | Additional information: Clone REA506 displays negligible binding to Fc receptors.
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文献和实验该产品被引用文献
Li, Z. et al. (2012) Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation. Cell 151 (7): 1608–1616. | Yi, S. H. et al. (2014) Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation. Development 141 (4): 761–772. | Heddad Masson, M. et al. (2014) Foxa1 and Foxa2 regulate α-cell differentiation, glucagon biosynthesis, and secretion. Endocrinology 155 (10): 3781–3792.
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FoxA2 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
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