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- 详细信息
- 技术资料
- 免疫原:
CD49d
- 亚型:
rat IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
R1-2
- 标记物:
PE-Vio 770
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 靶点:
CD49d
- 抗体英文名:
CD49d Antibody, anti-mouse
- 抗体名:
CD49d Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Detection of mouse CD49d+ cellsThe monoclonal antibody R1-2 reacts with mouse CD49d, a 150 kDa Integrin family member, also known as integrin α4 chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin ß or ß1 (CD29) forming the complex VLA4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). Together with the ß7 integrin, CD49d forms the heterodimer LPAM-1, which is a ligand for the mucosal vascular addressin (MAdCAM-1).
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CD49d Antibody, anti-mouse, PE-Vio® 770, 30 µg in 1 mL
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