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- 详细信息
- 技术资料
- 免疫原:
CD284
- 亚型:
mouse IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
HTA125
- 标记物:
PE
- 适应物种:
human, other
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry
- 浓度:
1:11
- 靶点:
CD284
- 抗体英文名:
CD284 Antibody, anti-human
- 抗体名:
CD284 Antibody, anti-human
- 规格:
30 tests in 300 µL
Detection of human CD284+ cellsClone HTA125 reacts with CD284, a type I transmembrane signaling receptor also known as Toll-like receptor 4 (TLR4). Toll-like receptors are a family of pattern recognition receptors detecting the presence and characteristics of an infection and induce appropriately tailored innate and adaptive immune responses. TLR4 associates with its co-receptor MD-2. Together with the lipopolysaccharide (LPS)-binding protein (LBP) and CD14, this complex is responsible for signaling upon LPS recognition. TLR4 is expressed on monocytes and myeloid dendritic cells. Low levels are expressed on B cells and granulocytes in human peripheral blood. HTA125 is able to block LPS-induced signaling and recognizes predominantly human TLR4 associated with MD-2.
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CD284 Antibody, anti-human, PE, 30 tests in 300 µL
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