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- 详细信息
- 技术资料
- 免疫原:
F4/80
- 亚型:
recombinant human IgG1
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
REA126
- 标记物:
APC
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
human cell line
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), 3D-Immunofluorescence, Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 靶点:
F4/80
- 抗体英文名:
F4/80 Antibody, anti-mouse, REAfinity™
- 抗体名:
F4/80 Antibody, anti-mouse, REAfinity™
- 规格:
150 µg in 1 mL
Identification and enumeration of F4/80+ cells by flow cytometryClone REA126 recognizes F4/80, a member of epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 is considered as one of the most specific cell-surface markers for murine macrophages. F4/80 is a seven-span transmembrane molecule with a large extracellular, multiple EGF module–containing domain. Constitutive and high expression of F4/80 is found on most resident tissue macrophages, including the spleen, microglia in the brain, Kupffer's cells in the liver, and Langerhans cells in the skin. In addition, the expression of F4/80 can also be regulated depending on the physiological status of the cell. F4/80 molecule is required for the differentiation of antigen-specific CD8+ Tregs and is involved in inducing peripheral immune tolerance. No specific ligand for F4/80 has been reported so far. | Additional information: Clone REA126 displays negligible binding to Fc receptors. |
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F4/80 Antibody, anti-mouse, APC, REAfinity™, 150 µg in 1 mL
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