- 询价
- Miltenyi Biotec
- 德国
- 130-127-874
- 2025年12月09日
- Flow cytometry
- human cell line
- human
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- 详细信息
- 技术资料
- 免疫原：
DCIR
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA329
- 标记物：
APC-Vio 770
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 靶点：
DCIR
- 抗体英文名：
DCIR Antibody, anti-human, REAfinity™
- 抗体名：
DCIR Antibody, anti-human, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of DCIR+ cells by flow cytometryClone REA329 recognizes the human dendritic cell immunoreceptor (DCIR) antigen, a single-pass type II membrane protein with a single carbohydrate recognition domain which is also known as C-type lectin domain family 4 member A (CLEC4A) or lectin-like immunoreceptor (LLIR). DCIR is expressed on dendritic cells (DCs), monocytes, macrophages, B lymphocytes, and granulocytes, but not detected on NK and T cells. DCIR is strongly expressed by DC derived from blood monocytes cultured with GM-CSF and IL-4. It is mostly expressed by monocyte-related rather than Langerhans cell related DC obtained from CD34+ progenitor cells. Finally, DCIR expression is down-regulated by signals inducing DC maturation such as CD40 ligand, LPS, or TNF-α. Thus, DCIR is differentially expressed on DC depending on their origin and stage of maturation/activation. | Additional information: Clone REA329 displays negligible binding to Fc receptors. |
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DCIR Antibody, anti-human, APC-Vio® 770, REAfinity™, 100 tests in 200 µL
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