- 询价
- Miltenyi Biotec
- 德国
- 130-105-295
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human, mouse
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 免疫原：
c-Cbl pY700
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA362
- 标记物：
APC
- 适应物种：
human, mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:11
- 靶点：
c-Cbl pY700
- 抗体英文名：
c-Cbl pY700 Antibody, anti-human/mouse, REAfinity™
- 抗体名：
c-Cbl pY700 Antibody, anti-human/mouse, REAfinity™
- 规格：
30 tests in 300 µL
Identification and enumeration of c-Cbl pY700+ cells by flow cytometryClone REA362 recognizes the human and mouse c-Cbl antigen phosphorylated at tyrosine 700 (pY700). The multifunctional adaptor Cbl acts as a negative regulator of intracellular signaling induced by engagement of cell-surface receptors. The RING finger domain of Cbl has E3 ubiquitin ligase activity that catalyses ubiquitilation and targeting of critical signaling molecules to lysosomal or proteosomal degradation. Moreover, Cbl regulates endocytosis of receptor tyrosine kinase and activity of other signaling proteins through a proteolysis-independent mechanism. c-Cbl unlike the other Cbl proteins contains only a short proline-rich region and no C-terminal leucine zipper-like region. The c-Cbl adapter protein is expressed in the cytoplasm in all tissues, with especially high levels of expression in hematopoietic cells. | Additional information: Clone REA362 displays negligible binding to Fc receptors. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
c-Cbl pY700 Antibody, anti-human/mouse, APC, REAfinity™, 30 tests in 300 µL
询价
