- 询价
- Miltenyi Biotec
- 德国
- 130-101-496
- 2025年12月09日
- Intracellular flow cytometry
- human cell line
- human, mouse
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- 详细信息
- 技术资料
- 免疫原：
BLNK pY84
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA240
- 标记物：
PE
- 适应物种：
human, mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Intracellular flow cytometry
- 浓度：
1:10
- 靶点：
BLNK pY84
- 抗体英文名：
BLNK pY84 Antibody, anti-human/mouse, REAfinity™
- 抗体名：
BLNK pY84 Antibody, anti-human/mouse, REAfinity™
- 规格：
100 tests in 1 mL
Identification and enumeration of BLNK pY84+ cells by flow cytometryClone REA240 recognizes BLNK protein phosphorylated at tyrosine 84. BLNK is an approximately 50 KDa src homology 2 and 3 domain–containing protein that bears homology to another adaptor molecule called SLP-76 and serves as a central linker/adaptor protein involved in bridging B cell receptor–associated kinase activation with downstream signaling pathways. BLNK is phosphorylated upon BCR stimulation and couples protein tyrosine kinase (PTK) Syk activation to downstream components such as Grb2, Vav, Nck, and phospholipase C (PLC)-γ2. Further, BLNK has been shown to play a role in the activation of all three classes of mitogen-activated protein kinases (MAPKs). Expression of BLNK is found in B cell lineage cells. | Additional information: Clone REA240 displays negligible binding to Fc receptors. |
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BLNK pY84 Antibody, anti-human/mouse, PE, REAfinity™, 100 tests in 1 mL
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