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- 详细信息
- 技术资料
- 免疫原:
CD49f
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
GoH3
- 标记物:
APC
- 适应物种:
human, mouse, non-human primate, other
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
- 浓度:
1:11
- 靶点:
CD49f
- 抗体英文名:
CD49f Antibody, anti-human/mouse
- 抗体名:
CD49f Antibody, anti-human/mouse
- 规格:
30 tests in 300 µL
Detection of human, mouse, or non-human primate CD49f+ cellsClone GoH3 reacts with CD49f, a 120 kDa transmembrane glycoprotein also known as α6 integrin. Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells. Clone GoH3 antibody has been reported to block laminin binding in vitro and to block integrin α6 function in vivo.
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CD49f Antibody, anti-human/mouse, APC, 30 tests in 300 µL
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