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- 详细信息
- 技术资料
- 免疫原:
CD49d
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
MRα4-1
- 标记物:
PE
- 适应物种:
rat
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 靶点:
CD49d
- 抗体英文名:
CD49d Antibody, anti-rat
- 抗体名:
CD49d Antibody, anti-rat
- 规格:
150 µg in 1 mL
Identification and enumeration of CD49d+ cells by flow cytometryClone MRα4-1 recognizes the mouse CD49d antigen, a 150 kDa integrin family member, also known as integrin α4 chain or VLA-4α chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin ß or ß1 (CD29) forming the complex VLA-4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA-4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3–mediated signaling.
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CD49d Antibody, anti-rat, PE, 150 µg in 1 mL
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