CD44 Antibody, anti-mouse, FITC, 30 µg in 200 µL

CD44 Antibody, anti-mouse, FIT

C, 30 µg in 200 µL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-126-116
  • 2025年12月09日
  • Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
  • rat
  • mouse, non-human primate, other
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    • 详细信息
    • 技术资料
    • 免疫原

      CD44

    • 亚型

      rat IgG2bκ

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,2-8℃

    • 克隆性

      IM7.8.1

    • 标记物

      FITC

    • 适应物种

      mouse, non-human primate, other

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      rat

    • 应用范围

      Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry

    • 浓度

      1:50

    • 靶点

      CD44

    • 抗体英文名

      CD44 Antibody, anti-mouse

    • 抗体名

      CD44 Antibody, anti-mouse

    • 规格

      30 µg in 200 µL

    Discrimination of mouse antigen-experienced T cells (CD44high) from naive T cells (CD44low)Mouse CD44 is also known as Pgp-1, HCELL, HUTCH-I, HCAM, HERMES, and Ly-24. Clone IM7 reacts with murine CD44, an 80–95 kDa membrane glycoprotein. It is expressed by a variety of hematopoetic and non-hematopoetic cells. Different isoforms are generated by alternative splicing. Clone IM7 reacts with all isoforms and both allelic forms of CD44. CD44 functions as a receptor for hyaluronic acid (HA) and mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 expression is upregulated on naive T cells upon activation and high CD44 expression is maintained on memory T cells. Therefore, CD44 is often used to discriminate CD44highantigen-experienced T cells from CD44low (CD62L+) naive T cells.

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