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- 详细信息
- 技术资料
- 免疫原:
CD39
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
MZ18-23C8
- 标记物:
APC
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Immunocytochemistry
- 浓度:
1:11
- 靶点:
CD39
- 抗体英文名:
CD39 Antibody, anti-human
- 抗体名:
CD39 Antibody, anti-human
- 规格:
30 tests in 300 µL
Detection of human or non-human primate CD39+ regulatory T cells and other CD39-expressing cellsThe CD39 antibody specifically recognizes the membrane-bound human CD39 antigen, which is expressed on an effector/memory-like subset of FoxP3+ regulatory T cells. CD39 is an ectonucleotidase and catalyzes the hydrolysis of extracellular nucleotides, for example, ATP. In concert with CD73, which is an ecto-5’-nucleotidase, this can lead to the production of adenosine. High extracellular ATP concentrations indicate tissue injury and cell death and induce various pro-inflammatory responses in immune cells. | Through its enzymatic activity, CD39 can contribute to the suppressive function of regulatory T cells, for example, by eliminating extracellular ATP or by generating adenosine, which has suppressive effects on various immune cells.
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CD39 Antibody, anti-human, APC, 30 tests in 300 µL
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