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- 详细信息
- 技术资料
- 免疫原:
CD357 (GITR)
- 亚型:
rat IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
DTA-1
- 标记物:
PE
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Functional assay
- 浓度:
1:10
- 靶点:
CD357 (GITR)
- 抗体英文名:
CD357 (GITR) Antibody, anti-mouse
- 抗体名:
CD357 (GITR) Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Detection of mouse regulatory T cells and activated T cellsClone DTA-1 specifically recognizes mouse CD357, also known as glucocorticoid-induced TNF-receptor (GITR) or TNFRSF18, a member of the TNF receptor superfamily. It is expressed at low levels on resting T lymphocytes and at high levels on CD4+CD25+ regulatory T cells (Tregs). Activation of T cells upregulates GITR expression. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production, as well as MAPKs and NF-κB activation. GITR plays an important role in the function of CD4+CD25+ Tregs.
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CD357 (GITR) Antibody, anti-mouse, PE, 30 µg in 1 mL
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