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- 详细信息
- 技术资料
- 免疫原:
CD283 (TLR3)
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
TLR 3.7
- 标记物:
Biotin
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 靶点:
CD283 (TLR3)
- 抗体英文名:
CD283 (TLR3) Antibody, anti-human
- 抗体名:
CD283 (TLR3) Antibody, anti-human
- 规格:
100 tests in 1 mL
Identification and enumeration of CD283 (TLR3)+ cells by flow cytometryThe monoclonal antibody TLR 3.7 reacts with CD283, also known as toll-like receptor 3 (TLR3). Toll-like receptors are a family of pattern recognition receptors that have evolved to detect components of foreign pathogens referred to as pathogenassociated molecular patterns. TLR3 is a single-pass type I membrane protein expressed exclusively in intracellular vesicles, such as the endoplasmic reticulum (ER), endosomes, lysosomes, and endolysosomes, where it recognizes microbial dsRNA. Multiple cell types are known to express TLR3 including dendritic cells, keratinocytes, and neurons. TLR3 activates via the TRIF-dependent pathway antiviral immune responses through the production of type I interferon and inflammatory cytokines, suggesting that TLR3 has an essential role in the prevention of viral infection.
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CD283 (TLR3) Antibody, anti-human, Biotin, 100 tests in 1 mL
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