- 询价
- Miltenyi Biotec
- 德国
- 130-102-030
- 2025年12月09日
- Flow cytometry, Functional assay
- rat
- mouse
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- 详细信息
- 技术资料
- 免疫原：
CD275 (B7-H2)
- 亚型：
rat IgG2aκ
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
HK5.3
- 标记物：
Biotin
- 适应物种：
mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
rat
- 应用范围：
Flow cytometry, Functional assay
- 浓度：
1:10
- 靶点：
CD275 (B7-H2)
- 抗体英文名：
CD275 (B7-H2) Antibody, anti-mouse
- 抗体名：
CD275 (B7-H2) Antibody, anti-mouse
- 规格：
9 µg in 300 µL
Identification and enumeration of CD275 (B7-H2)+ cells by flow cytometryClone HK5.3 recognises murine CD275, which is also known as B7-H2 and ICOSL. CD275 is a type I membrane protein and belongs to the Ig superfamily, B7 family of costimulatory molecules. Expression of CD275 is found on antigen presenting cells such as B cells, dendritic cells, and monocytes. CD275 costimulates T cells upon binding to ICOS, which is expressed on activated T cells. In mouse, CD275 binds only ICOS, whereas in humans it can interact with other T cell costimulatory molecules, CD28 and CTLA-4. To appropriately regulate the activation of immune response, the ICOS-CD275 interaction can also lead to downregulation of CD275 expression which allows prevention of hyperreaction of T cells.
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CD275 (B7-H2) Antibody, anti-mouse, Biotin, 9 µg in 300 µL
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