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- 详细信息
- 技术资料
- 免疫原:
CD252 (OX40L)
- 亚型:
rat IgG2bκ
- 形态:
Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
- 保存条件:
避光,2-8℃
- 克隆性:
RM134L
- 标记物:
pure-functional grade
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Functional assay
- 靶点:
CD252 (OX40L)
- 抗体英文名:
CD252 (OX40L) Antibody, anti-mouse
- 抗体名:
CD252 (OX40L) Antibody, anti-mouse
- 规格:
500 µg in 0.5 mL
Unconjugated antibody for functional assaysClone RM134L recognizes CD252 (OX40L), a ligand of OX40 receptor, belonging to the TNF superfamily. Expression of CD252 can be induced on B cells, dendritic cells, macrophages, mast cells, natural killer (NK) cells, endothelial cells, and smooth muscle cells. Expression of the cognate receptor OX40 is found on activated CD4 cells, CD8 cells, regulatory T cells, NKT cells, NK cells, and neutrophils, but the function of OX40 signaling is extensively studied only in T cells. CD252 (OX40L)-OX40 interaction promotes the proliferation and surival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells (nTreg), and inhibits the generation of inducible Treg cells.
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CD252 (OX40L) Antibody, anti-mouse, pure-functional grade, 500 µg in 0.5 mL
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