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- 详细信息
- 技术资料
- 免疫原:
CD209 (DC-SIGN)
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
DCN47.5
- 标记物:
PE-Vio 770
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:50
- 靶点:
CD209 (DC-SIGN)
- 抗体英文名:
CD209 (DC-SIGN) Antibody, anti-human
- 抗体名:
CD209 (DC-SIGN) Antibody, anti-human
- 规格:
30 tests in 60 µL
Detection of CD209 (DC-SIGN) on human cellsClone DCN47.5 recognizes CD209 (Dendritic Cell Specific ICAM-3 Grabbing Non-integrin, DC-SIGN), a type II c-type lectin expressed in dermal and mucous tissue, lymphoid tissue such as tonsil, lymph node, spleen, and on monocyte-derived DCs (MoDCs). It is not expressed on DC subsets in peripheral blood, except for a subpopulation of CD14+ cells with a DC-like phenotype. | DC-SIGN acts as an adhesion receptor to facilitate interactions between DCs and T cells or DCs and endothelial cells. In addition, it serves as an antigen receptor mediating internalization of ligands for antigen presentation, binding virus such as HIV, HCMV, or Ebola as well as parasites, bacteria, or yeast. | HIV-1 uses this feature of DC-SIGN for efficient in -trans infection of CD4+ T cells.
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CD209 (DC-SIGN) Antibody, anti-human, PE-Vio® 770, 30 tests in 60 µL
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