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- 详细信息
- 技术资料
- 免疫原:
CD205 (DEC205)
- 亚型:
mouse IgG1κ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
HD30
- 标记物:
pure
- 适应物种:
human, non-human primate
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry
- 靶点:
CD205 (DEC205)
- 抗体英文名:
CD205 (DEC205) Antibody, anti-human
- 抗体名:
CD205 (DEC205) Antibody, anti-human
- 规格:
100 µg in 1 mL
Detection of human CD205 (DEC205)+ cells such as thymic epithelial cells and dendritic cellsClone HD30 detects the CD205 glycoprotein. CD205, also known as DEC205 or Ly-75, is a 210 kDa C-type lectin single-pass membrane protein (type I), which is highly expressed on thymic epithelial cells and dendritic cells. Unlike murine CD205, human CD205 is also found at low levels on other peripheral blood lymphocytes, e.g., monocytes, T cells, B cells, and NK cells. CD205 belongs to the macrophage mannose receptor family and acts as an endocytic receptor to uptake antigens, direct the captured antigens from the extracellular space to the antigen-processing compartment for antigen presentation on MHC class II and cross-presentation on MHC class I molecules. Another function of CD205 is the clearance of apoptotic cells, potentially an important pathway for the uptake of self-antigen in intrathymic and peripheral tolerance.
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CD205 (DEC205) Antibody, anti-human, pure, 100 µg in 1 mL
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