- 询价
- Miltenyi Biotec
- 德国
- 130-127-512
- 2025年12月09日
- Flow cytometry
- mouse
- human
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- 详细信息
- 技术资料
- 免疫原：
CD203c
- 亚型：
mouse IgG1κ
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
FR3-16A11
- 标记物：
PE
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
mouse
- 应用范围：
Flow cytometry
- 浓度：
1:50
- 靶点：
CD203c
- 抗体英文名：
CD203c Antibody, anti-human
- 抗体名：
CD203c Antibody, anti-human
- 规格：
30 tests in 60 µL
Detection of human basophils and mast cellsClone FR3-16A11 recognizes CD203c, a glycosylated type II transmembrane molecule that belongs to the family of ecto-nucleotide pyrophosphatase/ phosphodiesterase (E-NPP3) enzymes. Among hematopoietic cells, expression of CD203c is restricted to basophils as well as to mast cells and their precursors, and has been described as specific for this lineage. Protein and/or mRNA expression of CD203c has also been found in solid tissues such as uterus or prostate. Basophils and mast cells are key producers of mediators that drive the onset of inflammatory responses, e.g., in allergy. Allergen challenge leads to a rapid up-regulation of activation markers such as CD203c or CD63. Due to its restricted expression pattern, CD203c is discussed as a specific marker to monitor the allergen-induced activation of basophils, e.g., in flow cytometric basophil activation tests of the peripheral blood.
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CD203c Antibody, anti-human, PE, 30 tests in 60 µL
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