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- 详细信息
- 技术资料
- 免疫原:
CD181 (CXCR1)
- 亚型:
mouse IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
8F1
- 标记物:
PE
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
mouse
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:11
- 靶点:
CD181 (CXCR1)
- 抗体英文名:
CD181 (CXCR1) Antibody, anti-human
- 抗体名:
CD181 (CXCR1) Antibody, anti-human
- 规格:
100 tests in 1 mL
Identification and enumeration of CD181 (CXCR1)+ cells by flow cytometryClone 8F1 recognizes the human CD181 antigen, a multi-pass membrane protein also known as C-X-C chemokine receptor type 1 (CXCR1) or IL-8 receptor A (IL-8RA). CD181 is expressed as homodimer or heterodimer with CD182 (CXCR2) and found on granulocytes, NK cells, a subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. It is one of two high-affinity receptors for IL-8, a major mediator of immune and inflammatory responses implicated in many disorders, including tumor growth. IL-8, released in response to inflammatory stimuli, binds to the extracellular part of CD181. The ligand-activated intracellular signaling pathways results in neutrophil migration to the site of inflammation.
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CD181 (CXCR1) Antibody, anti-human, PE, 100 tests in 1 mL
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