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- 详细信息
- 技术资料
- 免疫原:
CD18
- 亚型:
rat IgG2aκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
M18/2
- 标记物:
APC-Vio 770
- 适应物种:
mouse
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry, Functional assay
- 浓度:
1:10
- 靶点:
CD18
- 抗体英文名:
CD18 Antibody, anti-mouse
- 抗体名:
CD18 Antibody, anti-mouse
- 规格:
9 µg in 300 µL
Identification and enumeration of CD18+ cells by flow cytometryClone M18/2 recognizes the CD18 antigen, a 95 kDa glycoprotein also known as integrin beta-2 (ITGB2). CD18 associates non-covalently with CD11a, CD11b, and CD11c to form LFA-1, Mac-1, and gp150/95, respectively and plays an important role in leukocytes adhesion. It is expressed on all leukocytes with NK and T cells showing higher density of surface expression. The CD18 integrin complexes bind CD54 (ICAM-1), CD102 (ICAM-2), CD50 (ICAM-3), iC3b, and fibrinogen. Heterodimers of CD18 with α subunits show different expression patterns on different leucocytes. Mice leucocytes lacking CD18 or expressing dysfunctional CD18 are defective in chemotaxis, phagocytosis, and homotypic aggregation.
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CD18 Antibody, anti-mouse, APC-Vio® 770, 9 µg in 300 µL
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