- 询价
- Miltenyi Biotec
- 德国
- 130-101-760
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- mouse
- human, non-human primate
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- 详细信息
- 技术资料
- 免疫原：
CD170 (Siglec-5)
- 亚型：
mouse IgG1κ
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
1A5
- 标记物：
APC
- 适应物种：
human, non-human primate
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
mouse
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:11
- 靶点：
CD170 (Siglec-5)
- 抗体英文名：
CD170 (Siglec-5) Antibody, anti-human
- 抗体名：
CD170 (Siglec-5) Antibody, anti-human
- 规格：
30 tests in 300 µL
Identification and enumeration of CD170 (Siglec-5)+ cells by flow cytometryClone 1A5 recognizes the CD170 antigen, a single-pass transmembrane protein member of the immunoglobulin superfamily, also known as sialic acid-binding Ig-like lectin 5 (siglec-5). CD170 is expressed on neutrophils, monocytes, dendritic cells, and subsets of tissue macrophages. It contains two tyrosine-based motifs in its cytoplasmic tail implicating signaling functions and forms a 140 kDa dimer on the cell surface. Tyrosine phosphorylation of CD170 leads to recruitment of the tyrosine phosphatases SHP-1 and SHP-2, which in turn efficiently inhibits FcεRI-mediated calcium fluxing and serotonin release. CD170 binds α 2-3– and α 2-6–linked sialic acid as well as glycophorin A, and is involved in cell adhesion.
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CD170 (Siglec-5) Antibody, anti-human, APC, 30 tests in 300 µL
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